Pharmaceutical Sciences – PY

[aayush_005]

Natural Products: Pharmacognosy & Phytochemistry – Chemistry, tests, isolation, characterization and estimation
of phytopharmaceuticals belonging to the group of Alkaloids, Glycosides, Terpenoids, Steroids, Bioflavanoids,
Purines, Guggul lipids. Pharmacognosy of crude drugs that contain the above constituents. Standardization of
raw materials and herbal products. WHO guidelines. Quantitative microscopy including modern techniques used
for evaluation. Biotechnological principles and techniques for plant development, Tissue culture.
Pharmacology: General pharmacological principles including Toxicology. Drug interaction. Pharmacology of drugs
acting on Central nervous system, Cardiovascular system, Autonomic nervous system, Gastro intestinal system
and Respiratory system. Pharmacology of Autocoids, Hormones, Hormone antagonists, chemotherapeutic agents
including anticancer drugs. Bioassays, Immuno Pharmacology. Drugs acting on the blood & blood forming
organs. Drugs acting on the renal system.
Medicinal Chemistry: Structure, nomenclature, classification, synthesis, SAR and metabolism of the following
category of drugs, which are official in Indian Pharmacopoeia and British Pharmacopoeia. Introduction to drug
design. Stereochemistry of drug molecules. Hypnotics and Sedatives, Analgesics, NSAIDS, Neuroleptics,
Antidepressants, Anxiolytics, Anticonvulsants, Antihistaminics, Local Anaesthetics, Cardio Vascular drugs –
Antianginal agents Vasodilators, Adrenergic & Cholinergic drugs, Cardiotonic agents, Diuretics, Antijypertensive
drugs, Hypoglycemic agents, Antilipedmic agents, Coagulants, Anticoagulants, Antiplatelet agents.
Chemotherapeutic agents – Antibiotics, Antibacterials, Sulphadrugs. Antiproliozoal drugs, Antiviral, Antitubercular,
Antimalarial, Anticancer, Antiamoebic drugs. Diagnostic agents. Preparation and storage and uses of official
Radiopharmaceuticals, Vitamins and Hormones. Eicosonoids and their application.
Pharmaceutics : Development, manufacturing standards Q.C. limits, labeling, as per the pharmacopoeal
requirements. Storage of different dosage forms and new drug delivery systems. Biopharmaceutics and
Pharmacokinetics and their importance in formulation. Formulation and preparation of cosmetics – lipstick, shampoo,
creams, nail preparations and dentifrices. Pharmaceutical calculations.
Pharmaceutical Jurisprudence: Drugs and cosmetics Act and rules with respect to manufacture, sales and
storage. Pharmacy Act. Pharmaceutical ethics.
Pharmaceutical Analysis: Principles, instrumentation and applications of the following: Absorption spectroscopy
(UV, visible & IR). Fluorimetry, Flame photometry, Potentiometry. Conductometry and Plarography. Pharmacopoeial
assays. Principles of NMR, ESR, Mass spectroscopy. X-ray diffraction analysis and different chromatographic
methods.
Biochemistry. Biochemical role of hormones, Vitamins, Enzymes, Nucleic acids, Bioenergetics. General principles
of immunology. Immunological. Metabolism of carbohydrate, lipids, proteins. Methods to determine, kidney &
liver function. Lipid profiles.
Microbiology : Principles and methods of microbio0logical assays of the Pharmacopoeia. Methods of preparation
of official sera and vaccines. Serological and diagnostics tests. Applications of microorganisms in Bio Conversions
and in Pharmaceutical industry.
Clinical Pharmacy : Therapeutic Drug Monitoring Dosage regimen in Pregnancy and Lactation, Pediatrics and
Geriatrics. Renal and hepatic impairment. Drug – Drug interactions and Drug – food interactions, Adverse Drug
reactions. Medication History, interview and Patient counseling.

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